UBXN1 抗体 (AA 262-312)
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Quick Overview for UBXN1 抗体 (AA 262-312) (ABIN7451534)
抗原
See all UBXN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 262-312
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原理
- Rabbit anti-UBXN1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 262 and 312
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亚型
- IgG
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anti-UBX Domain Protein 1 (UBXN1) antibody
UBXN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (AA 1-312) antibodyUBXN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (AA 215-264) antibodyUBXN1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 马, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (Middle Region) antibodyUBXN1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 马, 兔, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- UBXN1 (UBX Domain Protein 1 (UBXN1))
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别名
- UBXN1
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背景
- Background: UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.
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基因ID
- 51035
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NCBI登录号
- NP_056937
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UniProt
- Q04323
抗原
-
