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UBXN1 抗体 (AA 262-312)

This anti-UBXN1 antibody is a 兔 多克隆 antibody detecting UBXN1 in IP. Suitable for 人.
产品编号 ABIN7451534
发货至: 中国

Quick Overview for UBXN1 抗体 (AA 262-312) (ABIN7451534)

抗原

See all UBXN1 抗体
UBXN1 (UBX Domain Protein 1 (UBXN1))

适用

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宿主

  • 34
  • 1

克隆类型

  • 35
多克隆

标记

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This UBXN1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP)
  • 抗原表位

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    AA 262-312

    原理

    Rabbit anti-UBXN1 Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine

    纯化方法

    Affinity Purified

    免疫原

    between AA 262 and 312

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    UBXN1 (UBX Domain Protein 1 (UBXN1))

    别名

    UBXN1

    背景

    Background: UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.

    基因ID

    51035

    NCBI登录号

    NP_056937

    UniProt

    Q04323
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