电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SPRY2 抗体 (AA 75-125)

This anti-SPRY2 antibody is a 兔 多克隆 antibody detecting SPRY2 in IP. Suitable for 人.
产品编号 ABIN7451515
发货至: 中国

Quick Overview for SPRY2 抗体 (AA 75-125) (ABIN7451515)

抗原

See all SPRY2 抗体
SPRY2 (Sprouty Homolog 2 (SPRY2))

适用

  • 41
  • 24
  • 15
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1

宿主

  • 45
  • 3
  • 1
  • 1

克隆类型

  • 46
  • 4
多克隆

标记

  • 41
  • 3
  • 2
  • 2
  • 1
  • 1
This SPRY2 antibody is un-conjugated

应用范围

  • 43
  • 23
  • 23
  • 12
  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-125

    原理

    Rabbit anti-Sprouty 2 Antibody, Affinity Purified

    预测反应

    Mouse,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 75 and 125

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SPRY2 (Sprouty Homolog 2 (SPRY2))

    别名

    Sprouty 2

    背景

    Background: Sprouty 2 contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells sprouty 2 is transiently upregulated in response to fibroblast growth factor two. Sprouty 2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. Sprouty 2 interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. Sprouty 2 may play a role in alveoli branching during lung development as shown by a similar mouse protein [taken from NCBI Entrez Gene (Gene ID: 10253)].

    基因ID

    10253

    NCBI登录号

    NP_005833

    UniProt

    O43597

    途径

    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
You are here:
Chat with us!