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NIPBL 抗体 (AA 550-600)

This 兔 多克隆 anti-NIPBL antibody specifically detects NIPBL in IP. The antibody is reactive with 人 samples.
产品编号 ABIN7451484
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for NIPBL 抗体 (AA 550-600) (ABIN7451484)

抗原

See all NIPBL 抗体
NIPBL (Nipped-B like Protein (NIPBL))

适用

  • 16
  • 16
  • 7

宿主

  • 25
  • 3
  • 3
  • 1

克隆类型

  • 28
  • 4
多克隆

标记

  • 14
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NIPBL antibody is un-conjugated

应用范围

  • 13
  • 13
  • 10
  • 9
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 550-600

    原理

    Rabbit anti-NIPBL Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 550 and 600

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    NIPBL (Nipped-B like Protein (NIPBL))

    别名

    NIPBL

    背景

    Background: The NIPBL (Nipped B-like) gene was originally identified as a gene mutated in individuals with Cornelia de Lange syndrome (CdLS), a heterogenous developmental disorder associated with multiple anatomical malformations. The NIPBL protein product is also referred to as delangin. It has substantial homology to the D. melanogaster Nipped-B protein which is related to a family of chromosomal adherins that plays a role in sister chromatid adhesion, chromosome condensation, and DNA repair. A study of metaphase spreads from individuals positive and negative for NIPBL mutations revealed an association between NIPBL mutations and precocious sister chromatid separation. This result suggests a function for NIPBL that is similar to its homolog in drosophila.

    基因ID

    25836

    NCBI登录号

    NP_597677

    UniProt

    Q6KC79

    途径

    Sensory Perception of Sound, Stem Cell Maintenance
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