Multidrug-Resistance Like Protein 1 抗体 (AA 275-325)
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Quick Overview for Multidrug-Resistance Like Protein 1 抗体 (AA 275-325) (ABIN7451476)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 275-325
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原理
- Rabbit anti-MRP1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 275 and 325
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Multidrug-Resistance Like Protein 1 (MRP)
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别名
- MRP1
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背景
- Background: Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. MRP1 functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. MRP1 also transports glucuronides and sulfate conjugates of steroid hormones and bile salts [taken from NCBI Entrez Gene (Gene ID: 4363)].
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基因ID
- 4363
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NCBI登录号
- NP_004987
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UniProt
- P33527
抗原
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