PKC eta 抗体 (AA 300-350)
Quick Overview for PKC eta 抗体 (AA 300-350) (ABIN7451303)
抗原
See all PKC eta (PRKCH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-350
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原理
- Rabbit anti-PKC-eta Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 300 and 350
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亚型
- IgG
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anti-Protein Kinase C, eta (PRKCH) (AA 1-678) antibody
PRKCH 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-100) antibodyPRKCH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-683) antibodyPRKCH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 210-239), (N-Term) antibodyPRKCH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 355-614) antibodyPRKCH 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 35-84) antibodyPRKCH 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-683) antibodyPRKCH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (N-Term) antibodyPRKCH 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 517-566) antibodyPRKCH 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼, Pig, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (C-Term) antibodyPRKCH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-PKC-eta antibody ABIN7450569.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
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别名
- PKC-eta
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背景
- Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC-eta is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. PKC-eta can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene [taken from NCBI Entrez Gene (Gene ID: 5583)].
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基因ID
- 5583
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NCBI登录号
- NP_006246
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UniProt
- P24723
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途径
- Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
抗原
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