PITRM1 抗体 (AA 987-1037)
Quick Overview for PITRM1 抗体 (AA 987-1037) (ABIN7451174)
抗原
See all PITRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 987-1037
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原理
- Rabbit anti-PITRM1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 987 and 1037
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亚型
- IgG
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anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 758-1037) antibody
PITRM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) antibodyPITRM1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 1-534) antibodyPITRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 758-1037) antibodyPITRM1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 653-926) antibodyPITRM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 544-806) antibodyPITRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451174 has not performed satisfactorily when used for WB of PITRM1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PITRM1.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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别名
- PITRM1
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背景
- Background: Pitrilysin metalloproteinase 1 (PITRM1) is an ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. PITRM1 also degrades other unstructured peptides. It is specific for peptides in the range of 10 to 65 residues. It is able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. PTMRM shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference [taken from the Universal Protein Resource (UniProt) Q5JRX3].
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基因ID
- 10531
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UniProt
- Q5JRX3
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途径
- PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome
抗原
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