Cadherin 13 抗体 (AA 475-525)
Quick Overview for Cadherin 13 抗体 (AA 475-525) (ABIN7451103)
抗原
See all Cadherin 13 (CDH13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 475-525
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原理
- Rabbit anti-Cadherin 13/CDH13/T-cadherin Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 475 and 525
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451103 has not performed satisfactorily when used for WB of Cadherin 13/CDH13/T-cadherin in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Cadherin 13/CD.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Cadherin 13 (CDH13)
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别名
- Cadherin 13/CDH13/T-cadherin
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背景
- Background: Cadherin-13 is a member of the cadherin superfamily. Cadherin-13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. Cadherin-13 lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. Cadherin-13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis [taken from NCBI Entrez Gene (Gene ID: 1012)].
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基因ID
- 1012
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UniProt
- P55290
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途径
- EGFR Signaling Pathway, Cell-Cell Junction Organization
抗原
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