LZTS2 抗体 (C-Term)
Quick Overview for LZTS2 抗体 (C-Term) (ABIN7451099)
抗原
See all LZTS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-LZTS2 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- Between AA 660 and C-term
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451099 has not performed satisfactorily when used for WB of LZTS2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of LZTS2.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
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别名
- LZTS2
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背景
- Background: leucine zipper, putative tumor suppressor 2 (LZTS2) is az negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. It is a negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin [taken from the Universal Protein Resource (UniProt) Q9BRK4].
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基因ID
- 84445
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UniProt
- Q9BRK4
抗原
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