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FAM120A 抗体 (AA 1068-1118)

There is 1 publication for this product available. The 兔 多克隆 anti-FAM120A antibody is suitable to detect FAM120A in samples from 人 和 小鼠. It has been validated for WB 和 IP.
产品编号 ABIN7451012
发货至: 中国
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Quick Overview for FAM120A 抗体 (AA 1068-1118) (ABIN7451012)

抗原

See all FAM120A 抗体
FAM120A (Family with Sequence Similarity 120A (FAM120A))

适用

  • 11
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 9
  • 2

克隆类型

  • 9
  • 2
多克隆

标记

  • 11
This FAM120A antibody is un-conjugated

应用范围

  • 11
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1068-1118

    原理

    Rabbit anti-OSSA Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1068 and 1118

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:500 - 1:2,500

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • Lobo, Nowak, Fernandez, Correa Muler, Westholm, Huang, Fabrik, Huynh, Shcherbinina, Poyraz, Härtlova, Benhalevy, Angeletti, Sarshad: "Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference." in: Nucleic acids research, Vol. 52, Issue 16, pp. 9917-9935, (2024) (PubMed).

  • 抗原

    FAM120A (Family with Sequence Similarity 120A (FAM120A))

    别名

    OSSA

    背景

    Background: Oxidative stress-associated Src activator (OSSA) may participate in mRNA transport in the cytoplasm (by similarity). OSSA is a critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. It binds RNA and promotes the secretion of IGF-II. OSSA may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses [taken from the Universal Protein Resource (UniProt) Q9NZB2].

    基因ID

    23196

    NCBI登录号

    NP_055427

    UniProt

    Q9NZB2
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