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USP11 抗体 (AA 870-920)

This anti-USP11 antibody is a 兔 多克隆 antibody detecting USP11 in WB 和 IP. Suitable for 人.
产品编号 ABIN7450882
发货至: 中国

Quick Overview for USP11 抗体 (AA 870-920) (ABIN7450882)

抗原

See all USP11 抗体
USP11 (Ubiquitin Specific Peptidase 11 (USP11))

适用

  • 45
  • 12
  • 12
  • 1
  • 1

宿主

  • 37
  • 7
  • 1

克隆类型

  • 30
  • 15
多克隆

标记

  • 26
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This USP11 antibody is un-conjugated

应用范围

  • 31
  • 17
  • 12
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 870-920

    原理

    Rabbit anti-USP11 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 870 and 920

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    USP11 (Ubiquitin Specific Peptidase 11 (USP11))

    别名

    USP11

    背景

    Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 11 (USP11) is a member of this family. USP11 has been found to associate with several proteins and may have functions independent of its deubiquitinating activity. USP11 deubiquitinates and associates with the RanGTP-binding protein, RanBPM. It has also been found to associate with BRCA2 and participate in the BRCA2 DNA damage related pathway, however, it does not appear to be involved in BRCA2 deubiquitination. USP11 also appears to play a role in the regulation of the IKKalpha and p53 signaling pathway by a mechanism independent of it deubiquitination activity.

    基因ID

    8237

    UniProt

    P51784
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