Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2340-2390) 抗体
Quick Overview for Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2340-2390) 抗体 (ABIN7450766)
抗原
See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2340-2390
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原理
- Rabbit anti-SPTBN2/SCA5 Antibody, Affinity Purified
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预测反应
- Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 2340 and 2390
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
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别名
- SPTBN2/SCA5
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背景
- Background: SPTBN2/SCA5 is a member of the beta spectrin gene family and a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization. SPTBN2/SCA5 has been identified as a Golgi- and vesicle-associated spectrin. Mutations in SPTBN2/SCA5 cause spinocerebellar ataxia type 5 (SCA5), an autosomal dominant disease characterized by progressive incoordination of gait, hand, speech, and eye movements.
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基因ID
- 6712
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NCBI登录号
- NP_008877
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UniProt
- O15020
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途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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