SHARPIN 抗体 (AA 25-75)
Quick Overview for SHARPIN 抗体 (AA 25-75) (ABIN7450727)
抗原
See all SHARPIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-75
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原理
- Rabbit anti-SHARPIN Antibody, Affinity Purified
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预测反应
- Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 25 and 75
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))
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别名
- SHARPIN
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背景
- Background: Sharpin (Shank-associated RH domain-interacting protein) is a component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) Q9H0F6].
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基因ID
- 81858
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NCBI登录号
- NP_112236
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UniProt
- Q9H0F6
抗原
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