RBBP6 抗体 (AA 50-100)
Quick Overview for RBBP6 抗体 (AA 50-100) (ABIN7450638)
抗原
See all RBBP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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原理
- Rabbit anti-RBBP6 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 50 and 100
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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别名
- RBBP6
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背景
- Background: Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) Q7Z6E9].
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基因ID
- 5930
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UniProt
- Q7Z6E9
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途径
- Regulatory RNA Pathways
抗原
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