PYGL 抗体 (AA 797-847)
Quick Overview for PYGL 抗体 (AA 797-847) (ABIN7450622)
抗原
See all PYGL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 797-847
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原理
- Rabbit anti-PYGL Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 797 and 847
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PYGL (phosphorylase, Glycogen, Liver (PYGL))
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别名
- PYGL
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背景
- Background: Glycogen phosphorylase, liver form, (PYGL) encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues [taken from NCBI Entrez Gene (Gene ID: 5836)].
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基因ID
- 5836
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NCBI登录号
- NP_002854
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UniProt
- P06737
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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