Plexin A3 抗体 (AA 1050-1100)
The 兔 多克隆 anti-Plexin A3 antibody is suitable to detect Plexin A3 in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN7450574
发货至:
中国
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Quick Overview for Plexin A3 抗体 (AA 1050-1100) (ABIN7450574)
抗原
See all Plexin A3 (PLXNA3) 抗体
Plexin A3 (PLXNA3)
适用
人
宿主
兔
克隆类型
多克隆
标记
This Plexin A3 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunoprecipitation (IP)
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抗原表位
- AA 1050-1100
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原理
- Rabbit anti-Plexin-A3 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1050 and 1100
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亚型
- IgG
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anti-Plexin A3 (PLXNA3) (AA 440-453), (Extracellular) antibody
PLXNA3 适用: 小鼠 IHC, WB, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Plexin A3 (PLXNA3)
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别名
- Plexin-A3
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背景
- Background: Plexin-A3 is a coreceptor for SEMA3A and SEMA3F. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A3 plays a role in axon guidance in the developing nervous system. It regulates the migration of sympathetic neurons, but not of neural crest precursors. Plexin-A3 is required for normal dendrite spine morphology in pyramidal neurons. It may play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm [taken from the Universal Protein Resource (UniProt) P51805].
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基因ID
- 55558
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NCBI登录号
- NP_059984
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UniProt
- P51805
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途径
- Regulation of Cell Size
抗原
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