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PKC eta 抗体 (AA 633-683)

This 兔 多克隆 anti-PKC eta antibody specifically detects PKC eta in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7450569
发货至: 中国
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Quick Overview for PKC eta 抗体 (AA 633-683) (ABIN7450569)

抗原

See all PKC eta (PRKCH) 抗体
PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

适用

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宿主

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克隆类型

  • 55
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多克隆

标记

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This PKC eta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 633-683

    原理

    Rabbit anti-PKC-eta Antibody, Affinity Purified

    预测反应

    Rat

    纯化方法

    Affinity Purified

    免疫原

    Between AA 633 and 683

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

    别名

    PKC-eta

    背景

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC-eta is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. PKC-eta can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene [taken from NCBI Entrez Gene (Gene ID: 5583)].

    基因ID

    5583

    NCBI登录号

    NP_006246

    UniProt

    P24723

    途径

    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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