NUP85 抗体 (AA 575-625)
Quick Overview for NUP85 抗体 (AA 575-625) (ABIN7450515)
抗原
See all NUP85 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 575-625
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原理
- Rabbit anti-NUP85 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 575 and 625
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NUP85 (Nucleoporin 85kDa (NUP85))
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别名
- NUP85
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背景
- Background: Nucleoporin 85 (NUP85) is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex, it plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2 and seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade [taken from the Universal Protein Resource (UniProt) Q9BW27].
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基因ID
- 79902
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NCBI登录号
- NP_079120
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UniProt
- Q9BW27
抗原
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