MUM1 抗体 (AA 125-175)
Quick Overview for MUM1 抗体 (AA 125-175) (ABIN7450469)
抗原
See all MUM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-175
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原理
- Rabbit anti-MUM1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 125 and 175
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))
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别名
- MUM1
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背景
- Background: Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. MUM1 is required for efficient DNA repair and cell survival following DNA damage [taken from the Universal Protein Resource (UniProt) Q2TAK8].
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基因ID
- 84939
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NCBI登录号
- NP_116242
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UniProt
- Q2TAK8
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途径
- Chromatin Binding
抗原
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