ISR-beta 抗体 (AA 1332-1382)
Quick Overview for ISR-beta 抗体 (AA 1332-1382) (ABIN7450366)
抗原
See all ISR-beta 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1332-1382
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原理
- Rabbit anti-Insulin Receptor Beta Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1332 and 1382
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亚型
- IgG
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anti-Insulin Receptor beta (ISR-beta) (AA 801-900) antibody
ISR-beta 适用: 人, 大鼠, 小鼠 FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor beta (ISR-beta) (AA 1001-1100) antibodyISR-beta 适用: 人, 大鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor beta (ISR-beta) (pTyr1185) antibodyISR-beta 适用: 人, 大鼠, 小鼠 WB, IF (cc), IF (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor beta (ISR-beta) (pTyr1355) antibodyISR-beta 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ISR-beta (Insulin Receptor beta (ISR-beta))
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别名
- Insulin Receptor Beta
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背景
- Background: The insulin receptor is a receptor tyrosine kinase that mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates to stimulate uptake of glucose. The insulin receptor is synthesized as a single polypeptide that is cleaved to generate an alpha and beta subunit. The subunit structure of the insulin receptor consists of a tetramer of two alpha and two beta chains linked by disulfide bonds.
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基因ID
- 3643
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NCBI登录号
- NP_000199
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UniProt
- P06213
抗原
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