IMPA1 抗体 (AA 227-277)
Quick Overview for IMPA1 抗体 (AA 227-277) (ABIN7450359)
抗原
See all IMPA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 227-277
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原理
- Rabbit anti-IMPA1 Antibody, Affinity Purified
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预测反应
- Bovine,Pig,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 227 and 277
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亚型
- IgG
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anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibody
IMPA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6-F11 unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (C-Term) antibodyIMPA1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
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别名
- IMPA1
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背景
- Background: Inositol monophosphatase 1 (IMPA1) is an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorde [taken from NCBI Entrez Gene (Gene ID: 3612)].
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基因ID
- 3612
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UniProt
- P29218
抗原
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