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FOXO1 抗体 (C-Term)

This anti-FOXO1 antibody is a 兔 多克隆 antibody detecting FOXO1 in WB 和 IP. Suitable for 人.
产品编号 ABIN7450261
发货至: 中国

Quick Overview for FOXO1 抗体 (C-Term) (ABIN7450261)

抗原

See all FOXO1 抗体
FOXO1 (Forkhead Box O1 (FOXO1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FOXO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
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    C-Term

    原理

    Rabbit anti-FOXO1a Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine,Pig

    纯化方法

    Affinity Purified

    免疫原

    between AA 600 and C-term

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FOXO1 (Forkhead Box O1 (FOXO1))

    别名

    FOXO1a

    背景

    Background: Forkhead box protein 01A (FOXO1a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO1 is a transcription factor that integrates cell signals to mediate metabolism, the cell cycle, DNA repair, and response to cellular stress. In response to insulin, FOXO1 is phosphorylated by Akt and excluded from the nucleus and subsequently degraded. Over-expressed cytoplasmic FOXO1 interacts with TSC2 to cause its degradation and subsequent activation of the mTOR pathway, while nuclear localization inhibits the mTOR pathway.

    基因ID

    2308

    NCBI登录号

    NP_002006

    UniProt

    Q12778

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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