CDK13 抗体 (AA 1125-1175)
Quick Overview for CDK13 抗体 (AA 1125-1175) (ABIN7450096)
抗原
See all CDK13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1125-1175
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原理
- Rabbit anti-CDC2L5 Antibody, Affinity Purified
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预测反应
- Mouse,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 1125 and 1175
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
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别名
- CDC2L5
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背景
- Background: CDC2-like kinase 5 (CDC2L5) is a member of the cyclin-dependent serine/threonine protein kinase family that plays a central role in cell cycle control. The CDC2L5 cDNA was first identified as CHED (cholinesterase-related cell-division controller) and cloned serendipitously in a screen using a cholinesterase-specific oligonucleotide probe in search of a link between cholinergic signaling and hematopoietic cell division control. Recently, the understanding of the physiological function of CDC2L5 has become clearer. Due to its localization to speckles in the nucleoplasm and its interaction with the splicing protein, ASF/SF2-associated protein p32, it was suggested to play a role in mRNA processing. Further studies showed that overexpression of CDC2L5 altered mRNA splicing patterns, and that CDC2L5 associated with L-type cyclins known to be involved in alternative splicing. These results have led to the conclusion that CDC2L5 is part of a subfamily of cyclin dependent kinases that play a role in the regulation of alternative splicing.
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基因ID
- 8621
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NCBI登录号
- NP_003709
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UniProt
- Q14004
抗原
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