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CD2AP 抗体 (AA 689-639)

This anti-CD2AP antibody is a 兔 多克隆 antibody detecting CD2AP in WB 和 IP. Suitable for 人.
产品编号 ABIN7450093
发货至: 中国

Quick Overview for CD2AP 抗体 (AA 689-639) (ABIN7450093)

抗原

See all CD2AP (Cd2ap) 抗体
CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

适用

  • 26
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宿主

  • 27
  • 2
  • 1

克隆类型

  • 28
  • 2
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD2AP antibody is un-conjugated

应用范围

  • 18
  • 12
  • 11
  • 9
  • 6
  • 6
  • 6
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 689-639

    原理

    Rabbit anti-CD2AP Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 689 and 639

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

    别名

    CD2AP

    背景

    Background: CD2-associated protein (CD2AP) seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, it modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. It also controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. CD2AP may play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell and may anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis [taken from the Universal Protein Resource (UniProt) Q9Y5K6].

    基因ID

    23607

    NCBI登录号

    NP_036252

    UniProt

    Q9Y5K6
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