CD247 抗体 (AA 114-164)
Quick Overview for CD247 抗体 (AA 114-164) (ABIN7450091)
抗原
See all CD247 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-164
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原理
- Rabbit anti-CD247/CD3Z Antibody, Affinity Purified
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预测反应
- Mouse,Sheep,Pig
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纯化方法
- Affinity Purified
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免疫原
- Between AA 114 and 164
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CD247 (CD247 Molecule (CD247))
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别名
- CD247/CD3Z
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背景
- Background: T-cell surface glycoprotein CD3 zeta chain is encoded by the gene CD247, also known as CD3Z or CD3 zeta. CD247/CD3 zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response [taken from NCBI Entrez Gene (Gene ID: 919)].
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基因ID
- 919
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UniProt
- P20963
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
抗原
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