ACLY 抗体 (AA 350-400)
Quick Overview for ACLY 抗体 (AA 350-400) (ABIN7449939)
抗原
See all ACLY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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原理
- Rabbit anti-ACL Antibody, Affinity Purified
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预测反应
- Rat,Sheep,Bovine
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纯化方法
- Affinity Purified
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免疫原
- Between AA 350 and 400
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ACLY (ATP Citrate Lyase (ACLY))
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别名
- ACL
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背景
- Background: ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. ACL is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ACL may be involved in the biosynthesis of acetylcholine [taken from NCBI Entrez Gene (Gene ID: 47)].
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基因ID
- 47
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NCBI登录号
- NP_001087
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UniProt
- P53396
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途径
- Warburg Effect
抗原
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