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VASP 抗体 (AA 330-380)

This anti-VASP antibody is a 兔 多克隆 antibody detecting VASP in WB 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7449856
发货至: 中国

Quick Overview for VASP 抗体 (AA 330-380) (ABIN7449856)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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  • 1
人, 小鼠

宿主

  • 109
  • 19
  • 2

克隆类型

  • 103
  • 27
多克隆

标记

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  • 1
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This VASP antibody is un-conjugated

应用范围

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  • 5
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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    • 15
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    • 5
    • 5
    • 5
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    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 330-380

    原理

    Rabbit anti-VASP Antibody, Affinity Purified

    预测反应

    Dog

    纯化方法

    Affinity Purified

    免疫原

    Between AA 330 and 380

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    VASP

    背景

    Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG [taken from NCBI Entrez Gene (Gene ID: 7408)].

    基因ID

    7408

    NCBI登录号

    NP_003361

    UniProt

    P50552

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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