VASP 抗体 (AA 330-380)
Quick Overview for VASP 抗体 (AA 330-380) (ABIN7449856)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 330-380
-
原理
- Rabbit anti-VASP Antibody, Affinity Purified
-
预测反应
- Dog
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 330 and 380
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
-
别名
- VASP
-
背景
- Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG [taken from NCBI Entrez Gene (Gene ID: 7408)].
-
基因ID
- 7408
-
NCBI登录号
- NP_003361
-
UniProt
- P50552
-
途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
抗原
-