MED24 抗体 (AA 939-989)
Quick Overview for MED24 抗体 (AA 939-989) (ABIN7449847)
抗原
See all MED24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 939-989
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原理
- Rabbit anti-TRAP100/MED24 Antibody, Affinity Purified
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预测反应
- Rat,Chicken
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纯化方法
- Affinity Purified
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免疫原
- between AA 939 and 989
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MED24 (Mediator Complex Subunit 24 (MED24))
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别名
- TRAP100/MED24
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背景
- Background: TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development.
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基因ID
- 9862
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NCBI登录号
- NP_055630
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UniProt
- O75448
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity
抗原
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