FOXM1 抗体 (AA 713-763)
Quick Overview for FOXM1 抗体 (AA 713-763) (ABIN7449736)
抗原
See all FOXM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 713-763
-
原理
- Rabbit anti-FOXM1 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 713 and 763
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- FOXM1 (Forkhead Box M1 (FOXM1))
-
别名
- FOXM1
-
背景
- Background: FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.
-
基因ID
- 2305
-
NCBI登录号
- NP_973731
-
UniProt
- Q08050
-
途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-