NLRP2 抗体 (AA 625-675)
Quick Overview for NLRP2 抗体 (AA 625-675) (ABIN7449676)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 625-675
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原理
- Rabbit anti-NBS1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 625 and 675
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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别名
- NBS1
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背景
- Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.
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基因ID
- 4683
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NCBI登录号
- NP_002476
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UniProt
- O60934
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途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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