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Recombinant CD8 alpha 抗体 (AA 185-235)

This anti-CD8 alpha antibody is a 兔 单克隆 antibody detecting CD8 alpha in FACS, IHC, WB, IF (p) 和 mIF. Suitable for 人.
产品编号 ABIN7449561
发货至: 中国

Quick Overview for Recombinant CD8 alpha 抗体 (AA 185-235) (ABIN7449561)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

克隆位点

BLR044F
  • 抗原表位

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    AA 185-235

    原理

    Rabbit anti-CD8 alpha Recombinant Monoclonal Antibody [BLR044F]

    免疫原

    between AA 185 and 235 (C-term)

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    WB: 17:40:00

    限制

    仅限研究用
  • 浓度

    250 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8 alpha

    背景

    Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain [taken from NCBI Entrez Gene (Gene ID: 925)].

    基因ID

    925

    NCBI登录号

    NP_001759

    UniProt

    P01732

    途径

    TCR Signaling
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