Recombinant CD8 alpha 抗体 (AA 185-235)
Quick Overview for Recombinant CD8 alpha 抗体 (AA 185-235) (ABIN7449561)
抗原
See all CD8 alpha (CD8A) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 185-235
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原理
- Rabbit anti-CD8 alpha Recombinant Monoclonal Antibody [BLR044F]
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免疫原
- between AA 185 and 235 (C-term)
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亚型
- IgG
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应用备注
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 17:40:00
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8 alpha
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背景
- Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain [taken from NCBI Entrez Gene (Gene ID: 925)].
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基因ID
- 925
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NCBI登录号
- NP_001759
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UniProt
- P01732
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途径
- TCR Signaling
抗原
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