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Recombinant CD16 抗体 (AA 21-201)

This anti-CD16 antibody is a 兔 单克隆 antibody detecting CD16 in WB, IHC 和 ICC. Suitable for 人.
产品编号 ABIN7449423
发货至: 中国

Quick Overview for Recombinant CD16 抗体 (AA 21-201) (ABIN7449423)

抗原

See all CD16 抗体
CD16

抗体类型

Recombinant Antibody

适用

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  • 2

宿主

  • 127
  • 27
  • 20
  • 1

克隆类型

  • 147
  • 26
  • 1
单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

BLR163J
  • 抗原表位

    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-201

    原理

    Rabbit anti-CD16 Recombinant Monoclonal Antibody [BLR163J]

    免疫原

    residues 21-201 (ECD)

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CD16

    别名

    CD16

    背景

    Background: CD16A (FCGR3A) is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. CD16A is highly similar to another nearby gene (CD16B, FCGR3B) located on chromosome 1. CD16A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas CD16B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. [taken from NCBI Entrez Gene (Gene ID: 2214)].

    基因ID

    2214, 2215

    NCBI登录号

    NP_000560

    UniProt

    P08637, O75015

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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