Apo-B100 抗体
This anti-Apo-B100 antibody is a 山羊 多克隆 antibody detecting Apo-B100 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7449339
发货至:
中国
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Quick Overview for Apo-B100 抗体 (ABIN7449339)
抗原
See all Apo-B100 抗体
Apo-B100
(Apoprotein B100 (Apo-B100))
适用
人
宿主
山羊
克隆类型
多克隆
标记
This Apo-B100 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
克隆位点
A07
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原理
- Goat anti-Human ApoB-100 Antibody Affinity Purified
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纯化方法
- Antigen Affinity Purified
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免疫原
- Human Apolipoprotein B100
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亚型
- IgG
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anti-Apoprotein B100 (Apo-B100) (AA 4331-4567) antibody
Apo-B100 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoprotein B100 (Apo-B100) (AA 3365-3548) antibodyApo-B100 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:1,000 - 1:80,000
ELISA: 1:1,000 - 1:80,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- Apo-B100 (Apoprotein B100 (Apo-B100))
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别名
- ApoB-100
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背景
- ApoB exists in human plasma in two isoforms, ApoB-48 (Chen et al., 1987) and Apo B-100 (Wei et al., 1985, Yang et al., 1986a, 1989a,b, 1990, Chen et al., 1986, Yang et al., 1990, Yang and Pownall, 1992). Apo B-100 is the major physiological ligand for the LDL receptor. Apo B-100 is a large monomeric protein, containing 4536 amino acids (m.w. 515 kDa, Yang et al., 1986b). Apo B-100 is synthesized in the liver and is required for the assembly of VLDL. It is found in LDL and VLDL after the removal of the Apo A, E and C. Apo B-48 is present in chylomicrons and their remnants. It is essential for the intestinal absorption of dietary lipids. Apo B levels correlate with the risk of coronary disease. The Apo B protein is directly involved in the retention of LDL with the arterial wall (Olofsson and Boren, 2012). Apo B-48 is synthesized in the small intestine. It comprises approximately half of the N-terminal region of ApoB-100 and is the result of posttranscriptional mRNA editing by a stop codon in the intestine not found in the liver.
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基因ID
- 338
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UniProt
- P04114
抗原
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