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APOE 抗体 (Biotin)

This Biotin-conjugated 山羊 多克隆 anti-APOE antibody (Clone B10) specifically detects APOE in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7449331
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOE 抗体 (Biotin) (ABIN7449331)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

  • 121
  • 92
  • 59
  • 2
  • 2
  • 2
  • 1
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宿主

  • 122
  • 33
  • 9
  • 2
  • 1
山羊

克隆类型

  • 111
  • 55
多克隆

标记

  • 77
  • 18
  • 10
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  • 3
  • 3
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  • 3
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  • 3
  • 3
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This APOE antibody is conjugated to Biotin

应用范围

  • 125
  • 57
  • 49
  • 39
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  • 7
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  • 1
Western Blotting (WB), ELISA

克隆位点

B10
  • 原理

    Goat anti-Human Apo E [B10] Antibody Biotin Conjugated

    免疫原

    Human Apolipoprotein E

    亚型

    IgG
  • 应用备注

    WB: 1:1,000 - 1:8,000

    ELISA: 1:1,000 - 1:8,000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    ApoE

    背景

    Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

    基因ID

    348

    NCBI登录号

    NP_000032

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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