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Apo-B100 抗体 (HRP)

This anti-Apo-B100 antibody is a 山羊 多克隆 antibody detecting Apo-B100 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7449329
发货至: 中国

Quick Overview for Apo-B100 抗体 (HRP) (ABIN7449329)

抗原

See all Apo-B100 抗体
Apo-B100 (Apoprotein B100 (Apo-B100))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This Apo-B100 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA

克隆位点

H06
  • 原理

    Goat anti-Human Apo B-100 [H06] Antibody HRP Conjugated

    免疫原

    Human Apolipoprotein B100

    亚型

    IgG
  • 应用备注

    WB: 1:1,000 - 1:8,000

    ELISA: 1:1,000 - 1:8,000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    50 mM PBS, 0.1 M NaCl, and 0.01 % Thiomersal, pH 7.4

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Apo-B100 (Apoprotein B100 (Apo-B100))

    别名

    ApoB-100

    背景

    Background: ApoB exists in human plasma in two isoforms, ApoB-48 (Chen et al., 1987) and Apo B-100 (Wei et al., 1985, Yang et al., 1986a, 1989a,b, 1990, Chen et al., 1986, Yang et al., 1990, Yang and Pownall, 1992). Apo B-100 is the major physiological ligand for the LDL receptor. Apo B-100 is a large monomeric protein, containing 4536 amino acids (m.w. 515 kDa, Yang et al., 1986b). Apo B-100 is synthesized in the liver and is required for the assembly of VLDL. It is found in LDL and VLDL after the removal of the Apo A, E and C. Apo B-48 is present in chylomicrons and their remnants. It is essential for the intestinal absorption of dietary lipids. Apo B levels correlate with the risk of coronary disease. The Apo B protein is directly involved in the retention of LDL with the arterial wall (Olofsson and Boren, 2012). Apo B-48 is synthesized in the small intestine. It comprises approximately half of the N-terminal region of ApoB-100 and is the result of posttranscriptional mRNA editing by a stop codon in the intestine not found in the liver.

    基因ID

    338

    NCBI登录号

    NP_000375

    UniProt

    P04114
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