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CSN3 抗体 (AA 325-375)

The 兔 多克隆 anti-CSN3 antibody is suitable to detect CSN3 in samples from 人. It has been validated for WB.
产品编号 ABIN7449263
发货至: 中国
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Quick Overview for CSN3 抗体 (AA 325-375) (ABIN7449263)

抗原

See all CSN3 抗体
CSN3 (Casein kappa (CSN3))

适用

  • 18
  • 13
  • 2
  • 2

宿主

  • 28
  • 3

克隆类型

  • 29
  • 2
多克隆

标记

  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSN3 antibody is un-conjugated

应用范围

  • 26
  • 13
  • 8
  • 8
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 325-375

    原理

    Rabbit anti-CSN3 Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 325 and 375

    亚型

    IgG
  • 应用备注

    1:2,000 - 1:20,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CSN3 (Casein kappa (CSN3))

    别名

    CSN3

    背景

    Background: CSN3 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. The CSN also possesses kinase activity. CSN3 is the kinase associated with the CSN complex that phosphorylates signal transducers such as I-kappa-Balpha, p105, and c-Jun. Human CSN3 maps to the Smith-Magenis syndrome locus. Microdeletions in this locus results in mental retardation, skeletal abnormalities, sleep disorder, and neurobehavior anomalies.

    基因ID

    8533

    NCBI登录号

    NP_003644

    UniProt

    Q9UNS2
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