Syntaxin 17 抗体 (AA 150-200)
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Quick Overview for Syntaxin 17 抗体 (AA 150-200) (ABIN7449258)
抗原
See all Syntaxin 17 (STX17) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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原理
- Rabbit anti-STX17 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- Between AA 150 and 200
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亚型
- IgG
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应用备注
- 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Syntaxin 17 (STX17)
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别名
- STX17
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背景
- Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355) [taken from the Universal Protein Resource (UniProt) P56962].
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基因ID
- 55014
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UniProt
- P56962
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途径
- Synaptic Vesicle Exocytosis
抗原
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