SETDB1 抗体 (AA 1125-1175)
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北京 101111
Quick Overview for SETDB1 抗体 (AA 1125-1175) (ABIN7449256)
抗原
See all SETDB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1125-1175
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原理
- Rabbit anti-SETDB1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1125 and 1175
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亚型
- IgG
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应用备注
- 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
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别名
- SETDB1
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背景
- Background: SETDB1 (SET domain, bifurcated 1) is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family that functions as a histone and DNA methyltransferase. SETDB1 was identified through its interaction with ERG (ets-related gene) and KAP1 (KRAB-associated protein1) and was later demonstrated to interact with HDAC1/2 (histone deacetylase 1/2), DNA methyltransferase 3s (DNMT3s), mSin3A/3B, HP1, and MBD1. SETDB1 is suggested to play a role in transcriptional repression important to early development.
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基因ID
- 9869
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NCBI登录号
- NP_036564
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UniProt
- Q15047
抗原
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