电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PDE12 抗体 (AA 559-609)

This anti-PDE12 antibody is a 兔 多克隆 antibody detecting PDE12 in WB. Suitable for 人.
产品编号 ABIN7449244
发货至: 中国

Quick Overview for PDE12 抗体 (AA 559-609) (ABIN7449244)

抗原

See all PDE12 抗体
PDE12 (Phosphodiesterase 12 (PDE12))

适用

  • 20
  • 11
  • 10
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 25
  • 1

克隆类型

  • 26
多克隆

标记

  • 18
  • 3
  • 2
  • 1
  • 1
  • 1
This PDE12 antibody is un-conjugated

应用范围

  • 26
  • 13
  • 11
  • 8
  • 8
  • 4
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 559-609

    原理

    Rabbit anti-PDE12 Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine

    纯化方法

    Affinity Purified

    免疫原

    Between AA 559 and 609

    亚型

    IgG
  • 应用备注

    1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PDE12 (Phosphodiesterase 12 (PDE12))

    别名

    PDE12

    背景

    Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system [taken from the Universal Protein Resource (UniProt) Q6L8Q7].

    基因ID

    201626

    UniProt

    Q6L8Q7
You are here:
Chat with us!