p107 抗体 (AA 1018-1068)
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北京 101111
Quick Overview for p107 抗体 (AA 1018-1068) (ABIN7449079)
抗原
See all p107 (RBL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1018-1068
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原理
- Rabbit anti-RBL1 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1018 and 1068
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亚型
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibody
RBL1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 适用: 人, 小鼠, Cow, 马, Pig, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (N-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- 6 - 15 μL/mg lysate
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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别名
- RBL1
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背景
- Background: Retinoblastoma-like protein 1 (RBL1) is a key regulator of entry into cell division. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. RBL1 recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. It controls histone H4 'Lys-20' trimethylation. RBL1 probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. It is a potent inhibitor of E2F-mediated trans-activation. RBL1 forms a complex with adenovirus E1A and with SV40 large T antigen and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RBL1 may act as a tumor suppressor [taken from the Universal Protein Resource (UniProt) P28749].
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基因ID
- 5933
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UniProt
- P28749
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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