LZTFL1 抗体 (AA 249-299)
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Quick Overview for LZTFL1 抗体 (AA 249-299) (ABIN7449064)
抗原
See all LZTFL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 249-299
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原理
- Rabbit anti-LZTFL1 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 249 and 299
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亚型
- IgG
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应用备注
- 15-20 μL/mg lysate
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))
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别名
- LZTFL1
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背景
- Background: LZTFL1 is a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in its gene cause a form of Bardet-Biedl Syndrome, a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This protein may also function as a tumor suppressor, possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. [provided by RefSeq, Feb 2013] [taken from NCBI Entrez Gene (Gene ID: 54585)].
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基因ID
- 54585
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UniProt
- Q9NQ48
抗原
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