RBBP5 抗体 (C-Term)
Quick Overview for RBBP5 抗体 (C-Term) (ABIN7449051)
抗原
See all RBBP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-RbBP5 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 500 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
ICC: 1:250 - 1:1,000
WB: 1:10,000 - 1:25,000
ChIP: 1 - 3 μg as per Dou et al., Nat Struct Mol Biol 13 (8):713-719, 2006. Previous lots of this antibody have performed in this application.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))
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别名
- RbBP5
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背景
- Background: Retinoblastoma binding protein 5 (RbBP5) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. RbBP5 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, ASH2L,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX. RbBP5 is also one of many proteins that bind the Retinoblastoma tumor suppressor protein, pRb.
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基因ID
- 5929
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NCBI登录号
- NP_005048
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UniProt
- Q15291
抗原
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