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WDR77 抗体 (AA 292-342)

This 兔 多克隆 antibody specifically detects WDR77 in IHC 和 IF (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7449034
发货至: 中国
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Quick Overview for WDR77 抗体 (AA 292-342) (ABIN7449034)

抗原

See all WDR77 抗体
WDR77 (WD Repeat Domain 77 (WDR77))

适用

  • 40
  • 15
  • 5
  • 3
  • 3
  • 3
  • 1
  • 1
人, 小鼠

宿主

  • 27
  • 13

克隆类型

  • 27
  • 13
多克隆

标记

  • 29
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WDR77 antibody is un-conjugated

应用范围

  • 26
  • 15
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 292-342

    原理

    Rabbit anti-WDR77/MEP50 IHC Antibody, Affinity Purified

    预测反应

    Orangutan,Monkey,Chimpanzee,Northern white-cheeked gibbon

    纯化方法

    Affinity Purified

    免疫原

    Between AA 292 and 342

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:50 - 1:500

    IHC: 1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    WDR77 (WD Repeat Domain 77 (WDR77))

    别名

    WDR77/MEP50

    背景

    Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.

    基因ID

    79084

    NCBI登录号

    NP_077007

    UniProt

    Q9BQA1

    途径

    Ribonucleoprotein Complex Subunit Organization
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