NPM1 抗体 (AA 250-294)
Quick Overview for NPM1 抗体 (AA 250-294) (ABIN7448992)
抗原
See all NPM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-294
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原理
- Rabbit anti-NPM1 IHC Antibody, Affinity Purified
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预测反应
- Rat,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Crab-eating macaque,Northern white-cheeked gibbon,Naked mole rat,Chinese hamster,Small-eared galago
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纯化方法
- Affinity Purified
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免疫原
- Between AA 250 and 294
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亚型
- IgG
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应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 100 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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别名
- NPM1
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背景
- Background: Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia [taken from the Universal Protein Resource (UniProt) P06748].
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基因ID
- 4869
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NCBI登录号
- NP_002511
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UniProt
- P06748
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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