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USP1 抗体 (AA 450-500)

This anti-USP1 antibody is a 兔 多克隆 antibody detecting USP1 in IHC. Suitable for 人.
产品编号 ABIN7448850
发货至: 中国

Quick Overview for USP1 抗体 (AA 450-500) (ABIN7448850)

抗原

See all USP1 抗体
USP1 (Ubiquitin Specific Peptidase 1 (USP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This USP1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 450-500

    原理

    Rabbit anti-USP1 IHC Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Zebra finch,Ferret,Northern white-cheeked gibbon,Crab-eating macaque,Thirteen-lined ground squirrel,Little brown bat,Naked mole rat,Small-eared galago,White-tufted-ear marmoset

    纯化方法

    Affinity Purified

    免疫原

    Between AA 450 and 500

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    USP1 (Ubiquitin Specific Peptidase 1 (USP1))

    别名

    USP1

    背景

    Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 1 (USP1) has been found to play a role in the Fanconi anemia DNA repair pathway. USP1 specifically removes monoubiquitination from the Fanconi anemia D2 (FANCD2) protein and from the proliferating cell nuclear antigen (PCNA). Deubiquitination of FANCD2 and PCNA is critical to their role in the DNA damage response and DNA crosslink repair.

    基因ID

    7398

    NCBI登录号

    NP_003359

    UniProt

    O94782
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