MAPKAP1 抗体 (C-Term)
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北京 101111
Quick Overview for MAPKAP1 抗体 (C-Term) (ABIN7448795)
抗原
See all MAPKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-Sin1 IHC Antibody, Affinity Purified
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预测反应
- Rat,Chicken,Turkey,Sheep,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Tasmanian devil,Crab-eating macaque,Zebra finch,Small-eared galago,Chinese hamster,Naked mole rat,Gray short-tailed opossum,Thirteen-lined ground squirrel,West Indian ocean coelacanth,Little brown bat,Duckbill platypus
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纯化方法
- Affinity Purified
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免疫原
- Between AA 470 and C-term
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 8-236) antibody
MAPKAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 370-486) antibodyMAPKAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 100-150) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 1-290) antibodyMAPKAP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 85-102) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 马, 绵羊, Bat, 猴, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 100 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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别名
- Sin1
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背景
- Background: Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling.
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基因ID
- 79109
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NCBI登录号
- NP_001006618
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UniProt
- Q9BPZ7
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途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
抗原
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