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PUS1 抗体 (AA 377-427)

This anti-PUS1 antibody is a 兔 多克隆 antibody detecting PUS1 in IHC. Suitable for 人.
产品编号 ABIN7448747
发货至: 中国

Quick Overview for PUS1 抗体 (AA 377-427) (ABIN7448747)

抗原

See all PUS1 抗体
PUS1 (Pseudouridylate Synthase 1 (PUS1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PUS1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 377-427

    原理

    Rabbit anti-PUS1 IHC Antibody, Affinity Purified

    预测反应

    Orangutan,Gorilla,Chimpanzee,White-tufted-ear marmoset,Northern white-cheeked gibbon

    纯化方法

    Affinity Purified

    免疫原

    Between AA 377 and 427

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PUS1 (Pseudouridylate Synthase 1 (PUS1))

    别名

    PUS1

    背景

    Background: Pus1 (pseudouridylate synthase 1) is an enzyme that converts uridine to pseudouridine in non-coding RNA substrates. Pus1 modifies uridines at specific positions in a subset of tRNAs. Pseudouridylation is known to affect the structure of tRNAs and stabilize base-stacking and base-pairing in the anticodon loop. Pus1 activity is important for proper folding and function of tRNAs. Pus1 has also been shown to pseudouridylate SRA (steroid receptor RNA activator) and function as a coactivator. Defects in pseudouridylation are associated with the human disease, MLASA (myopathy with lactic acidosis and sideroblastic anemia), an autosomal recessive oxidative phosphorylataion disorder specific to skeletal muscle and bone marrow.

    基因ID

    80324

    NCBI登录号

    NP_079491

    UniProt

    Q9Y606
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