PRCC 抗体 (AA 125-175)
This anti-PRCC antibody is a 兔 多克隆 antibody detecting PRCC in IHC. Suitable for 人 和 小鼠.
Quick Overview for PRCC 抗体 (AA 125-175) (ABIN7448740)
抗原
See all PRCC 抗体
PRCC
(Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This PRCC antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
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抗原表位
- AA 125-175
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原理
- Rabbit anti-PRCC IHC Antibody, Affinity Purified
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预测反应
- Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon
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纯化方法
- Affinity Purified
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免疫原
- Between AA 125 and 175
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亚型
- IgG
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anti-Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC) (C-Term) antibody
PRCC 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC) (C-Term) antibodyPRCC 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PRCC (Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC))
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别名
- PRCC
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背景
- Background: In a subset of papillary renal cell carcinomas, a t(X,1)(p11,q21) chromosome translocation has been repeatedly reported and is thought to be the cause of the cancer. As a result of the translocation, the transcription factor TFE3 on the X chromosome becomes fused to the PRCC (papillary renal cell carcinoma translocation-associated) gene on chromosome 1. The fused gene results in the fusion of N-terminal proline-rich region of the protein encoded by this gene to the entire TFE3 protein. This protein has been shown to interact with the mitotic checkpoint protein MAD2B, which suggests that the dominant-negative effect of the fusion protein with TFE3 may lead to a mitotic checkpoint defect [taken from NCBI GeneID:5546].
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基因ID
- 5546
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NCBI登录号
- NP_005964
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UniProt
- Q92733
抗原
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