MTA3 抗体 (AA 400-450)
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北京 101111
Quick Overview for MTA3 抗体 (AA 400-450) (ABIN7448677)
抗原
See all MTA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-450
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原理
- Rabbit anti-MTA3 IHC Antibody, Affinity Purified
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预测反应
- Orangutan,Monkey,Chimpanzee,White-tufted-ear marmoset,Crab-eating macaque,Northern white-cheeked gibbon,Small-eared galago
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纯化方法
- Affinity Purified
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免疫原
- Between AA 400 and 450
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亚型
- IgG
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anti-Metastasis Associated 1 Family, Member 3 (MTA3) (Internal Region) antibody
MTA3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 3 (MTA3) (AA 416-515) antibodyMTA3 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3B3 unconjugated
anti-Metastasis Associated 1 Family, Member 3 (MTA3) (AA 432-481) antibodyMTA3 适用: 人, 小鼠, 大鼠, 马, 兔, 犬, 豚鼠, 猴, 小鸡, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 3 (MTA3) (C-Term) antibodyMTA3 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 3 (MTA3) antibodyMTA3 适用: 人 DB 宿主: 小鼠 Monoclonal 428C2a unconjugated
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))
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别名
- MTA3
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背景
- Background: MTA3 (metastasis-associated protein 3) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA3 is a member of a family of proteins (MTA1-3) differentially expressed in metastatic breast cancer cells. MTA3 functions as a repressor of the transcription factor Snail, a factor involved in epithelial to mesenchymal transitions. MTA3 expression is estrogen dependent in breast cancer cells. Studies show that ERalpha selectively bind the MTA3 promoter in an SP1-dependent fashion to stimulate MTA3 gene transcription.
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基因ID
- 57504
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NCBI登录号
- NP_001317371
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UniProt
- Q9BTC8
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途径
- Chromatin Binding
抗原
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