General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) 抗体
The 兔 多克隆 anti-General Transcription Factor 3C Polypeptide 3 antibody (ABIN7448586) specifically detects General Transcription Factor 3C Polypeptide 3 in IHC.
The antibody is reactive with 人 samples.
产品编号 ABIN7448586
发货至:
中国
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Quick Overview for General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) 抗体 (ABIN7448586)
抗原
General Transcription Factor 3C Polypeptide 3 (GTF3C3)
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC)
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抗原表位
- AA 475-525
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原理
- Rabbit anti-GTF3C3/TFIII1C102 IHC Antibody, affinity purified
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预测反应
- Mouse,Rat,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Crab-eating macaque,African elephant,Ferret,Little brown bat,Zebra finch,Naked mole rat,Green anole,Northern white-cheeked gibbon,Tasmanian devil,White-tufted-ear marmoset,Gray short-tailed opossum,Small-eared galago
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纯化方法
- Affinity Purified
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免疫原
- Between AA 475 and 525
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 100 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- General Transcription Factor 3C Polypeptide 3 (GTF3C3)
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别名
- GTF3C3/TFIIIC102
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背景
- Background: General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.
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基因ID
- 9330
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NCBI登录号
- NP_036218
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UniProt
- Q9Y5Q9
抗原
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