DGCR8 抗体 (AA 1-50)
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北京 101111
Quick Overview for DGCR8 抗体 (AA 1-50) (ABIN7448526)
抗原
See all DGCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-DGCR8 IHC Antibody, Affinity Purified
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预测反应
- Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1 and 50
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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别名
- DGCR8
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背景
- Background: DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs [taken from the Universal Protein Resource (UniProt) Q8WYQ5].
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基因ID
- 54487
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NCBI登录号
- NP_073557
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UniProt
- Q8WYQ5
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途径
- Regulatory RNA Pathways
抗原
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